详情介绍
胶原蛋白II型牛源 进口试剂 现货供应 25mg/瓶 1200元
英文名称:Collagen Type II
货号:C7806
CAS号:9007-34-5
品牌:Sigma
规格:25mg
胶原蛋白II型牛源 进口试剂 产品描述:
胶原蛋白II型/Collagen Type II/来源于牛鼻膜/SIGMA C7806,100%
性状 | 白色冻干粉 |
溶解性 | aqueous acid: soluble |
保存温度 | 2-8°C |
Preparation Note
An acid soluble collagen soluble in dilute acetic acid at pH 3.0 (5 mg/ml), yielding an opalescent, colorless solution.
Collagen Type II is a triple helix composed of three α1(II) strands.
Application
Collagen-type II has been investigated for its importance in haemostasis. Two peptides, CB8 and CB11, are sites of plaet binding and activation on collagen-type 2. Collagen-type 2 has also been used as a model for arthritis in animals, where FR140423, a selective cyclooxygenase (COX)-2 inhibitor, has shown an anti-inflammatory effect without gastric lesions that may occur with treatment via indomethacin.
Collagen Type II is sometimes used to induce an animal model of rheumatoid arthritis. However, under conditions leading to formation of reactive oxygen species, the subjects develop tolerance for auto-antibodies. This is an unusual situation of ROS having a favorable effect.
现货供应 25mg/瓶 1200元